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KMID : 0361020070500060486
Korean Journal of Otolaryngology - Head and Neck Surgery
2007 Volume.50 No. 6 p.486 ~ p.490
Clinical Usefulness of Vestibular Evoked Myogenic Potential in Unilateral Meniere¡¯s Disease
Lee Jong-Cheol

Yoon Tae-Hyun
Chung Jong-Woo
Ahn Joong-Ho
Kim Jong-Yang
Kim Yun-Kyung
Abstract
Background & Objectives: Because the saccule, next to the cochlea, is the second most frequent site of hydrops formation, we evaluated whether vestibular evoked myogenic potential (VEMP) responses can reflect the diagnosis and the stage of Meniere¡¯s disease.

Subjects & Methods: Retrospectively, we analyzed the results of VEMP in 40 patients (11 men and 29 women) with unilateral definite Meniere¡¯s disease. All subjects underwent VEMP testing using ipsilateral 500 Hz-tone burst sound with 90 dBnHL (rise/fall time=2 msec, plateau time=3 msec).

Results: VEMP was present in 92.5% of Meniere¡¯s affected ear (37/40). The latency of p13 of affected ears in patients with Meniere¡¯s disease was significantly prolonged than that of normal ears in the control group (p=0.05). However, no relationship was found in latencies of p13, n23, and interpeak latency among groups classified by the stage of Meniere¡¯s disease. In the patients with Meniere¡¯s disease, the mean interaural amplitude difference (IAD) ratio was 23.9+/-16.9%. The IAD ratio of patients with Meniere¡¯s disease was larger than that of the control group, but it is statistically insignificant (p=0.133).

Conclusion: Prolonged p13 latency of VEMP was a pathognomic finding for Meniere¡¯s disease in this study.
KEYWORD
Vestibular Evoked Myogenic Potential, Meniere¡¯s Disease, Electrocochleography
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